Test May Spot Heart Attacks Before They Happen
Blood Test Looks for Type of Cell That Breaks Away From Artery Walls A new blood test could one day give doctors a critical head start on heart attacks, a small new study suggests. The test looks for cells that normally line the insides of blood vessels. When those cells, called endothelial cells, start to build up in the blood, researchers say they may be an early indicator of trouble. "When they start to leak and slough off into the blood, that's a really bad sign. They do that over the course of a few days to a couple of weeks before a heart attack occurs," says researcher Eric J. Topol, MD, a professor of genomics and director of the Scripps Translational Science Institute in La Jolla, Calif. "As they continue to slough off, they basically create a crack [in an artery wall]. A blood clot forms to seal the crack. That's what causes a heart attack," Topol says. Identifying Vulnerable Plaques In recent years, doctors have developed a new understanding o